
Pulmonary diseases with elevated pulmonary pressures can be divided into different categories based on the equation of motion. Part II: Breaking down the equation of motionīreaking down the equation of motion can narrow down our clinical differential and help make a better decision at the bedside. Total Pressure = Resistive Pressure + Distending Pressure The total pressure needed to get gas into the lung requires a resistive pressure plus a distending pressure.

Hopefully, it is easy to see that this equation is still just two parts. Or, if you prefer elastance over compliance (E = 1/C): The final equation with all substitutions: Transrespiratory pressure is a gradient between the sum of the pressure generated by the respiratory muscles (Pmusc) along with the pressure generated by the ventilator (Pvent) minus the alveolar pressure (Palv) or the PEEP. TRP = TAP + TTP TAP = R x F TTP = V/C ↓ TRP = R x F + V/C Transrespiratory Pressure = Transairway Pressure + Transthoracic Pressure

Now, with some quick substitutions for the definitions:
